One tablet contains: active substances: iron (III) testosterone propionate dosage polimaltozata – 318.2 mg, equivalent to elemental iron – 100.00 mg of folic acid – 350 mg; Excipients:lactose monohydrate – 765.5 mg of magnesium stearate – 12.50 mg mannitol – 84.00 mg colloidal silica – 22.00 mg, caramel – 66.00 mg sodium methyl parahydroxybenzoate – 2.66 mg sodium propilparagidproksibenzoat – 0.24 mg sodium chloride – 3.22 mg talc purified – 4.00 mg aspartame – 5.00 mg, flavor chocolate – 8.00 mg vanilla flavoring – 2.00 mg, purified water – of qs
Biofer preparation contains iron as iron testosterone propionate dosage polymaltose complex (III). This macromolecular complex is stable and does not separate iron in the form of free ions in the gastrointestinal tract. Biofera structure similar to a natural ferritin iron compound. Because of this similarity, iron (III) coming from the intestine into the blood by active transport. This property explains the inability of the drug overdose unlike simple iron salts, which absorption occurs along the concentration gradient. Suck iron and ferritin binds stored in the body, primarily in the liver. Then, in the bone marrow, it is included in the hemoglobin. Iron, part of the iron testosterone propionate dosage polymaltose complex (III), has no pro-oxidant properties, unlike simple iron salts. There is a correlation between the severity of iron deficiency and the level of its intake (the higher the severity of iron deficiency, the better the absorption). The most active absorption process occurs in the small intestine and duodenum.
Folic acid – vitamin B complex, stimulates erythropoiesis, is involved in the synthesis of amino acids, nucleic acids, purines, pyrimidines, exchangeable choline.
Biofer a chewable tablet dosage form does not cause staining of the teeth.
Indications for use:
- Treatment of latent and symptomatic iron deficiency (iron deficiency anemia).
- Prevention of iron and folic acid deficiency, including before, during and after pregnancy (lactation).
- Age up to 12 years
- Iron overload (hemochromatosis)
- Violation of iron utilization (lead anemia, sideroahrestical anemia, thalassemia)
- Nezhelezodefitsitnye anemia (hemolytic anemia, megaloblastic anemia caused by lack of vitamin B12).
Use during pregnancy:
In controlled studies in pregnant women during the second and third trimesters of pregnancy has not been observed undesirable effect of the drug on the mother and fetus. During the first trimester of pregnancy, the drug should be used only if the potential benefits of the drug in the mother than the potential risk to the fetus.
Dosage and administration:
Dosage and duration of treatment depend on the severity of iron deficiency. The daily dose can be taken once a day. Biofer tablets should be taken during or immediately after a meal. They can be chewed or swallowed whole.
Children older than 12 years, adults and nursing mothers:
treatment of symptomatic iron deficiency (iron deficiency anemia) – 1 tablet 1-3 times a day for 3-5 months to normalize the level of hemoglobin in the blood. Thereafter, the drug should continue for a few more months in order to recover the iron stores in the body (1 tablet per day).
Pregnant women should take 1 tablet Biofera 2-3 times a day until the normalization of hemoglobin. Then therapy should be continued in the mode 1 tablet 1 time a day, at least until delivery to the recovery of iron stores.
For the treatment of latent iron deficiency and prevention of iron deficiency and folic acid , patients should take 1 tablet 1 time a day,
The duration of the treatment of iron deficiency anemia is 3-5 months prior to the normalization of iron stores in the body, for pregnant women, as a minimum, prior to delivery.
The duration of treatment of latent iron deficiency is 1 -2 months.
Very rare (greater than or equal to 0.001% and less than 0.01%) may be marked signs of irritation of the gastrointestinal tract, such as a feeling of fullness, epigastric pressure, nausea, constipation or diarrhea, as well as allergies to folic acid .
Perhaps the dark stool staining caused by the release of nevsosavsheysya iron (clinical significance is not).
Overdose (intoxication) drug:
Until now, in cases of drug overdose, was not informed of any of intoxication, no signs of iron overload.
Interaction with other drugs:
Interactions with other drugs have been identified.
One Biofera tablet contains 0,06 bread units that need to be considered in the appointment of patients with diabetes.
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