Pharmacological properties compensates deficiency of exocrine pancreatic function, has proteolytic, amylolytic and lipolytic action.
Included in the pancreatin enzymes (lipase, alpha-amylase, trypsin, chymotrypsin) contribute to the breakdown of proteins to amino acids, fats to glycerol and fatty acids, starch to dextrins and monosaccharides.
Improves the functional state of the gastrointestinal tract, normalizes digestion.
Pancreatic enzymes are released from the dosage form in the alkaline environment of the small intestine because the protected from the action of gastric juice coating.
Therapeutic indications
Substitution treatment for exocrine pancreatic insufficiency: chronic pancreatitis, pancreatectomy, post-irradiation, indigestion, Remhelda syndrome (gastrocardiac syndrome), cystic fibrosis; flatulence, diarrhea non-infectious origin.
Violation of digestion (a condition after resection of the stomach and small intestine); to improve food digestion in patients with normal function of the gastrointestinal tract in the case of errors in the diet (eating fatty foods, large amounts of food, irregular meals) and prinarusheniyah chewing function, sedentary lifestyle, prolonged immobilization.
Preparing to X-ray and ultrasound examination of the abdominal cavity.
Contraindications
: Hypersensitivity to the drug, acute pancreatitis, exacerbation of chronic pancreatitis, children under 6 years.
Application of pregnancy and lactation .
The safety of pancreatin during pregnancy has been poorly studied. Application is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus. During lactation the use of pancreatin is not contraindicated.
Dosing and Administration
Inside. The drug is taken during or after a meal, without chewing and drinking non-alkaline liquid (water, fruit juices).
The dose is determined individually, depending on the degree of digestive disorders. Adults usually – 1 -. 2 testosterone propionate cycle 3 times a day
for children older than 6 years of drug applied by a doctor. The dose is determined individually.
Duration of treatment may vary from a few days (in case of violation of the digestive process due to errors in the diet) to several months or years (permanent replacement therapy if necessary).
Side effects:
Allergic reactions. Rarely – diarrhea, constipation, feeling of discomfort in the stomach, nausea (causal relationship of these reactions to the action of pancreatin has not been established, since these phenomena are symptoms of exocrine pancreatic insufficiency). With prolonged use at high doses may develop hyperuricosuria, hyperuricemia. In cystic fibrosis in the case of excess of the required dose of pancreatin may develop strictures (fibrous colonopathy) in the ileocecal department of the ascending colon.
In the application of pancreatin in high doses in children may cause perianal irritation and irritation of oral mucosa.
Overdose
Symptoms: hyperuricosuria, hyperuricemia. The children – constipation.
Treatment: removal of the drug, symptomatic therapy.
Interaction with other drugs
When using pancreatin may decrease the absorption of iron and folic acid. The simultaneous use of antacids containing calcium carbonate and / or magnesium hydroxide, can reduce the effectiveness of pancreatin.
Cautions
In cystic fibrosis do not recommend the use of pancreatin in high doses due to increased risk of stricture (fibrous colonopathy). The dose should be adequate to the number of enzymes required for fat absorption in view of the quality and quantity of food consumed.
Form release
Drops. According to 10 testosterone propionate cycle a contour bezgyachakova packing or 10 testosterone propionate cycle in blisters. 1, 2, 3, 5,10, or Valium contour cell package, along with instructions for use are placed in a pile of cardboard. anabolic steroids online shop
