Pharmacological action laxative. Irritating receptor apparatus intestine, has a direct effect on the intestinal mucosa, increasing its peristalsis and increasing the secretion of mucus in the colon.
The action comes after 6 hours when administered at bedtime taking 8-12 hours.
Not absorbed in the intestine. Is a prodrug in the alkaline hydrolysis medium to form a metabolite, is irritating to the mucous membrane of the gastrointestinal tract.
Hypotonic and atonic constipation (including constipation in the elderly, constipation after surgery and childbirth). Chair Regulation (haemorrhoids, proctitis, anal fissures). Preparation for surgery, instrumental and radiological investigations.
Hypersensitivity, intestinal obstruction, incarcerated hernia, acute inflammatory diseases of the abdominal cavity, abdominal pain of unknown origin, gastroenteritis, appendicitis, peritonitis, bleeding from the gastrointestinal tract, metrorrhagia, cystitis, spastic constipation, acute proctitis, acute hemorrhoids, children’s age up to 3 years, lactase deficiency, sucrase / isomaltase, lactose intolerance, fructose, glucose-galactose malabsorption (product contains lactose and sucrose).
Pregnancy, lactation, liver and / or kidney failure.
Dosage and administration
The tablets are taken orally 1 time a day at bedtime or 30 minutes before breakfast. Adults and children over 14 years – the drug is prescribed 1-3 tablets (5-15 mg) for reception;
Children aged 8-14 years 1-2 tablets (5-10 mg), children aged 3 to 7 years -. 1 tablet per intake (5 mg)
in preparation for surgery, instrumental and radiological investigations prescribed 2 tablets at night the day before the study and 2 tablets the night before the operation or investigation.
swallow whole tablets, without breaking, not liquid, squeezed small amounts of water.
of intestinal colic, diarrhea (dehydration, disruption of water and electrolyte metabolism, muscle weakness, convulsions, decreased blood pressure), abdominal pain, flatulence, and allergic reactions.
Overdose Symptoms: diarrhea, dehydration, disruption of water and electrolyte imbalance, hypokalemia, atonic colon. Treatment: symptomatic.
Interaction with other drugs
combined use of antacids can lead to premature dissolution of its shell and irritation of the stomach and duodenum.
It is not recommended to take simultaneously with milk and alkaline mineral water.
propionate testosterone should not be used in the treatment of chronic constipation for a long time (over 10 days).
If use of propionate testosterone will start bleeding from the rectum, the patient should be warned about the cessation of treatment.
As a result, use of the drug may violet staining of urine and feces.